Table 4.
Hospitalization by substance use disorder diagnoses among adult patients, stratified by the number of chronic conditions
| Prevalence of inpatient hospitalization, % | Number of chronic conditions* | ||||
|---|---|---|---|---|---|
| Overall | None | 1 | 2–3 | 4–9 | |
| N=211,880 | N=109,556 | N=43,279 | N=41,613 | N=17,432 | |
| % (95% CI) | % (95% CI) | % (95% CI) | % (95% CI) | % (95% CI) | |
| Overall | 30.3 (30.07–30.46) | 17.0 (16.79–17.23) | 25.5 (25.08–25.91) | 48.1 (47.62–48.58) | 82.8 (82.27–83.39) |
| Any substance use disorder | |||||
| Yes | 56.8 (56.22–57.38) | 33.0 (31.96–34.08) | 45.1 (43.85–46.32) | 64.2 (63.23–65.23) | 89.7 (88.83–90.42) |
| No | 26.2 (25.98–26.38) | 15.8 (15.61–16.05) | 22.2 (21.79–22.64) | 43.8 (43.22–44.29) | 79.5 (78.81–80.27) |
| Adjusted Odds Ratio (95% CI)† | 3.34 (3.25–3.44) | 3.48 (3.27–3.70) | 2.82 (2.65–2.99) | 2.48 (2.35–2.62) | 2.57 (2.32–2.85) |
| Tobacco use disorder | |||||
| Yes | 56.1 (55.48–56.82) | 30.9 (29.62–32.23) | 42.0(40.55–43.38) | 62.0 (60.84–63.11) | 88.6 (87.67–89.52) |
| No | 27.4 (27.20–27.60) | 16.4 (16.14–16.59) | 23.5 (23.08–23.93) | 45.3 (44.75–45.80) | 80.8 (80.11–81.47) |
| Adjusted Odds Ratio (95% CI)† | 2.94 (2.85–3.04) | 2.88 (2.67–3.11) | 2.25 (2.10–2.40) | 2.12 (2.01–2.24) | 2.13 (1.91–2.37) |
| Alcohol use disorder | |||||
| Yes | 63.9 (62.80–64.99) | 37.5 (35.53–39.58) | 58.1 (55.65–60.48) | 75.6 (73.73–77.32) | 93.8 (92.40–94.95) |
| No | 29.1 (28.85–29.25) | 16.6 (16.37–16.82) | 24.2 (23.84–24.66) | 46.6 (46.07–47.06) | 81.9 (81.29–82.48) |
| Adjusted Odds Ratio (95% CI)† | 4.07 (3.87–4.29) | 4.55 (4.07–5.10) | 4.47 (4.01–4.98) | 3.52 (3.17–3.90) | 3.49 (2.78–4.38) |
| Any drug use disorder | |||||
| Yes | 73.6 (72.62–74.52) | 51.3 (49.12–53.39) | 66.6 (64.27–68.82) | 79.8 (78.18–81.37) | 94.6 (93.54–95.50) |
| No | 28.5 (28.31–28.71) | 16.3 (16.12–16.56) | 23.9 (23.46–24.28) | 46.1 (45.63–46.62) | 81.3 (80.64–81.87) |
| Adjusted Odds Ratio (95% CI)† | 6.13 (5.81–6.46) | 6.99 (6.29–7.76) | 5.67 (5.09–6.33) | 4.83 (4.35–5.37) | 4.59 (3.75–5.61) |
Chronic conditions included hypertension, arthritis (osteoarthritis or rheumatoid), diabetes (type 1 or 2), chronic kidney disease, asthma, chronic obstructive pulmonary disease, ischemic heart disease, cancer (breast, endometrial, colorectal, lung, or prostate), and hepatitis viral B or C.
Each adjusted logistic regression model of inpatient hospitalization in relation to substance use disorder controlled for continuous age, sex, race/ethnicity, and mood or anxiety disorder diagnosis.
CI: confidence interval. Boldfaced: The estimate differed from the estimate without substance use disorder diagnosis (P<0.01) or P<0.01 for adjusted odds ratios.