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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Leuk Lymphoma. 2016 Aug 11;58(4):923–931. doi: 10.1080/10428194.2016.1213823

Table I.

EC50s for EBV-positive and EBV-negative B cell lines treated with ganetespib.

EC50 (nM)* SD EBV Latency State
LCLa 22.5 0.50 3
LCLb 19.5 1.5 3
BJAB 22.5 2.5 EBV negative
BL30 25.5 1.5 EBV negative
Akata 25.5 1.5 1
Kem1 37 2.0 1
Mutu I 26 4.0 1
SNT16 41.3 1.4 2
Jurkat 29.3 3.6 EBV-negative
*

EC50 is the effective concentration at which 50% of the cells were killed. Each value for the cells in the first seven rows represents the average of two experiments that were performed in triplicate, and for the last two rows each value is the average of three experiments; SD is the standard deviation of the data.