We investigated the imaging data further by fitting linear regressions adjusting for age at death, total intracranial
volume, and Braak stage. Our analysis showed that for cases with TDP-43 type-α had an estimated 11% (4%, 18%, p = 0.003)
smaller amygdala volume than TDP-43 type-β. For hippocampi, TDP-43 type-α cases had 14% (7%, 22%, p <0.001)
smaller volume than TDP-43 type-β cases. Plotted values are regression estimates and 95% confidence intervals.