. Author manuscript; available in PMC: 2020 Mar 1.

Published in final edited form as: Eur Radiol. 2018 Sep 21;29(3):1104–1113. doi: 10.1007/s00330-018-5719-1

Table 3.

Diagnostic parameters for clinical and MRI assessments (with 95% CI)

	Clinical^*	T2wMRI+DWI^*	T2wMRI+DWI+DCE^*	Clinical + T2wMRI+DWI+DCE^†
N	65	62	64	64
Sensitivity	55.0 (31.5, 76.9)	42.1 (20.3, 66.5)	52.6 (28.9, 75.6)	42.1 (20.3, 66.5)
Specificity	86.7 (73.2, 94.9)	76.7 (61.4, 88.2)	75.6 (60.5, 87.1)	95.6 (84.9, 99.5)
PPV	64.7 (38.3, 85.8)	44.4 (21.5, 69.2)	47.6 (25.7, 70.2)	80.0 (44.4, 97.5)
NPV	81.3 (67.4, 91.1)	75.0 (59.7, 86.8)	79.1 (64.0, 90.0)	79.6 (66.5, 89.4)
AUC	0.69 (0.54, 0.84)	0.66 (0.51,0.81)	0.68 (0.54, 0.83)	0.72 (0.57, 0.87)

Univariate analysis results; cutoff for calculation of diagnostic parameters was set between confidence levels 1 and 2 for clinical assessment and between levels 2 and 3 for MRI assessments.

^†

Multivariate analysis results; cutoff for calculation of diagnostic parameters was set at the maximum value of Youden’s J statistic, sensitivity + specificity − 1 = 0.38.