TABLE 3.

Percentage difference within groups from baseline to final 24 month intervention.

Variables	Δ MEX %	Within Group Effect P Value	Δ MET %	Within Group Effect P Value	Δ MEXMET %	Within Group Effect P Value
Body mass, kg	-3.6	0.008*	1.3	0.247	-1.1	0.005*
Waist circumference, cm	-4.2	0.004*	2.2	0.021*	-2.4	<0.001**
BMI, kg/m2	-2.7	0.007*	1.6	0.048*	-1.4	0.016*
Waist-to-hip ratio	-1.1	0.343	3.1	0.005*	0	0.246
Systolic BP, mmHg	-11.1	<0.001**	5.4	0.001*	0.7	<0.001**
Diastolic BP, mmHg	-11.3	<0.001**	2.5	0.416	-8.2	<0.001**
Total cholesterol, mg/dL	3.7	0.196	-8.3	0.489	-1.7	0.537
HDL-cholesterol, mg/dL	0	0.212	-11.6	0.492	0	0.214
LDL-cholesterol, mg/dL	-5.0	0.338	4.9	0.579	-3.9	0.328
Triglycerides, mg/dL	-21.2	0.019*	-0.8	0.763	2.3	0.547
Glycaemia, mg/dL	-12.3	0.003*	4.2	0.769	6.7	0.017*
HbA1c, %	-5.3	0.194	-0.7	0.908	0.01	0.579
6-min walk distance, m	17.7	<0.001**	-0.2	0.716	18.0	<0.001**

Data are expressed as mean (SD).

^*Differences between evaluations (P ≤ 0.05).

^**Differences between evaluations (P ≤ 0.001).