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. 2018 Nov 16;20:79–88. doi: 10.1016/j.molmet.2018.09.011

Figure 4.

Figure 4

Changes in total protein abundance and phosphorylation of signaling pathways in tibialis anterior muscle after FOXO1dn or FOXO3dn overexpression. (A) Quantification of protein abundance and phosphorylation of Akt signaling in tibialis anterior skeletal muscle after FOXO1dn transfection, or (B) FOXO3dn transfection. (C) Quantification of protein abundance and phosphorylation of mTOR, and protein synthesis signaling following FOXO1dn transfection, or (D) FOXO3dn transfection. (E) Representative western blots of the studied signaling cascades for FOXO1dn transfection, or (F) FOXO3dn transfection. Data are mean ± SEM. n = 11 mice, *p < 0.05 and **p < 0.01.