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Homozygous KI mice display a UCP1 deficiency phenotype in iBAT. A. Relative Ucp1 mRNA expression in interscapular BAT of WT, HET and KI mice, n = 6. Data were analyzed with One-way-ANOVA, ****P < 0.0001. B. Representative immunoblotting analysis of UCP1 and LUC proteins in interscapular BAT of WT, HET, and KI mice.
