Table 4.
Substrate | Isoenzyme | Incubation Time in Hours | Concentration | Reaction |
---|---|---|---|---|
Bupropion | CYP2B6 | 1 | 100 μM | Bupropion-hydroxylation |
Diclofenac | CYP2C9 | 1 | 9 μM | Diclofenac-4’-hydroxylation |
Testosterone | CYP3A4 | 1 | 50 μM | Testosterone-6β-hydroxylation |
Bufuralol | CYP2D6 | 2 | 9 μM | Bufuralol-1-hydroxylation |