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Analysis of: cell proliferation (A); total sGAG quantification (B); and sGAG/DNA quantification (C). Differences in relative expression of chondrogenic markers for COL1A1, COL2A1, SOX9, MMP3, MMP13, and VCAN (D–I) as determined by reverse transcriptase quantitative real-time PCR of chondrocytes cultured in hyperacute serum (HAS) and platelet-rich plasma (PRP) under normoxia (20% O2). Significant difference at * p < 0.05, ** p < 0.01, **** p < 0.0001; n = 6 biological replicates.
