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Analysis of determined catabolic inflammatory cytokines (IL-6 (A); and IL-1 β (B)) and anabolic growth factors (PDGF-BB (C); IGF-1 (D); BMP-2 (E); and TGF- β1 (F)) secreted by the chondrocytes during the culture period of 7 and 14 days under hypoxic conditions (4% O2). Significant difference at * p < 0.05; n = 6 biological replicates.
