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Effect of ciprofloxacin on the accumulation of [3H]-paclitaxel. The effect of ciprofloxacin on accumulation of [3H]-paclitaxel in SW620 and SW620/AD300 cells (A) and HEK293/pcDNA3.1 and HEK293/ABCB1 cells (B). Columns are the mean of triplicate determinations; the error bars represent the SD, * p < 0.05 versus the control group. Verapamil 10 μM is used as positive control for ABCB1-overexpressing cells.
