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. 2019 Jan 2;9(1):13. doi: 10.3390/biom9010013

Table 1.

Chemical structures and physicochemical properties of selected non-curcuminoids.

Name IUPAC Name Structure Molecular Weight (g/mol) Molecular Formula Physical and Chemical Properties
Ar-turmerone 6S-2-methyl-6-(4-methylphenyl) hept-2-en-4-one graphic file with name biomolecules-09-00013-i001.jpg 216.324 C15H20O Appearance: Yellowish oil
Boiling point: 326 °C
Melting point: 122 °C
Density: 0.945 g/cm3
Solubility: Hexane, petroleum ether, ethanol
β-Elemene (1S,2S,4R)-1-ethenyl-1-methyl-2,4-bis(prop-1-en-2-yl) cyclohexane graphic file with name biomolecules-09-00013-i002.jpg 204.357 C15H24 Appearance: Colorless to yellow clear liquid
Boiling point: 252 °C
Melting point: 98 °C
Density: 0.862 g/cm3
Solubility: Alcohol
γ- Elemene (1S,2S)-1-ethenyl-1-methyl-2-propan-2-ylidene-2-prop-1-en-2-yl) cyclohexane graphic file with name biomolecules-09-00013-i003.jpg 204.357 C15H24 Appearance: Clear and colorless liquid
Boiling point: 258.2 ± 40 °C at 760 mmHg
Melting point: 101.3 ± 22.2 °C
Density: 0.9 ± 0.1 g/cm3
Solubility: Alcohol
Furanodiene (5E,9E)-3,6,10-trimethyl-4,7,8,11-tetrahydrocyclodeca(b) furan graphic file with name biomolecules-09-00013-i004.jpg 216.324 C15H20O Appearance: White powder
Boiling point: 309.6 ± 11 °C at 760 mmHg
Melting point: 137.1 ± 6.1 °C
Density:0.9 ± 0.1 g/cm3
Solubility: Partially soluble in water
Calebin A (E-4-(4-hydroxy-3-methoxyphenyl)-2-oxobut-3-enyl)E-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate) graphic file with name biomolecules-09-00013-i005.jpg 384.384 C21H20O7 Appearance: White powder
Boiling point: 592.1 ± 50.0 °C at 760 mmHg
Melting point: 207.9 ± 23.6 °C
Density:1.3 ± 0.1 g/cm3
Solubility: Sparingly soluble in water
Germacrone (3E,7E)-3,7-dimethyl-10-propan-2-ylidenecyclodeca-3,7-dien-1-one graphic file with name biomolecules-09-00013-i006.jpg 218.34 C15H22O Appearance: White crystalline powder
Boiling point:666.52 °C
Melting point:347.53 °C
Density:0.9 ± 0.1 g/cm3
Solubility: Methanol
Cyclocurcumin (E)-2-(4-hydroxy-3-methoxyphenyl-6-(4-hydrox-3-methoxystyryl)-2H-pyra-4(3H)-one graphic file with name biomolecules-09-00013-i007.jpg 368.38 C21H20O6 Appearance: Yellow powder
Boiling point:571.9 ± 50.0 °C at 760 mmHg
Melting point: 202.6 ± 23.6 °C
Density:1.4 ± 0.1 g/cm3
Solubility: Ethanol and concentrated acetic acid
Bisacurone (6S)-6-((1R,4S,5S)-4,5-dihydroxy-4-methylcyclohex-2-en-1-yl) graphic file with name biomolecules-09-00013-i008.jpg 254.354 C15H24O3 Appearance: Bright orange powder
Boiling point: 377.7 ± 42.0 °C at 760 mmHg
Melting point: 196.4 ± 24.4 °C
Density: 1.1 ± 0.1 g/cm3
Solubility: Acetone and ethanol
Curcumol (1S,2S,5S,9S)-9-isopropyl-2-methyl-6-methylene-11-oxatricyclo(6.2.1.01,5)undecan-8-ol graphic file with name biomolecules-09-00013-i009.jpg 236.355 C15H24O2 Appearance: White crystals
Boiling point:334.5 °C
Melting point:134.69 C
Density:1.06 g/cm3
Solubility: DMSO in ethanol