Figure 1.

Blood pressure measurements in Ang II-treated mice. Wild type (WT) and apelin knockout (Apelin KO) mice at 12 months of age were continuously infused with either vehicle or angiotensin II (Ang II) for 2 weeks using osmotic minipumps (Ang II, 1 mg/kg/day) and measured for blood pressure using the tail-cuff method. Systolic (A), diastolic (B), and mean (C) blood pressures are shown. n = 4–6 per group. All values are mean ± SEM. † p < 0.1; * p < 0.05; ** p < 0.01. ns: not significant.