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. 2019 Jan 10;20(2):261. doi: 10.3390/ijms20020261

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Cytotoxicity of vanadium complexes on pancreas ductal adenocarcinoma cell lines (PANC-1, MIA PaCa2) and immortalized pancreas duct cells (hTERT-HPNE). Cytotoxicity was measured as cell viability using MTT (A) and NR (B) assays. Cells were exposed to four vanadium complexes (T1-T3 and C7 for comparison) at concentrations ranging from 1 to 100 µM for 48 h. The marked results were shown the least cytotoxic effect on hTERT-PHNE cell line. Data are mean ± SD of 3 separate determinations. * p < 0.05; ** p < 0.01; *** p < 0.001, as compared with untreated cells.

Cytotoxicity of vanadium complexes on pancreas ductal adenocarcinoma cell lines (PANC-1, MIA PaCa2) and immortalized pancreas duct cells (hTERT-HPNE). Cytotoxicity was measured as cell viability using MTT (A) and NR (B) assays. Cells were exposed to four vanadium complexes (T1-T3 and C7 for comparison) at concentrations ranging from 1 to 100 µM for 48 h. The marked results were shown the least cytotoxic effect on hTERT-PHNE cell line. Data are mean ± SD of 3 separate determinations. * p < 0.05; ** p < 0.01; *** p < 0.001, as compared with untreated cells.