Table 2.
Average size, polydispersity index (PI) and zeta potential (ZP) of liposomes, nutriosomes and EU-nutriosomes diluted and incubated at pH 1.2 and pH 7.0, at 37 °C. The measurements were carried out immediately after the dilution (t0) and after 2 h at pH 1.2 (t2h) or 6 h at pH 7.0 (t6h).
| Sample | Time | pH 1.2 | pH 7.0 | ||||
|---|---|---|---|---|---|---|---|
| Size (nm ± SD) | PI | ZP (mV ± SD) | Size (nm ± SD) | PI | ZP (mV ± SD) | ||
| Liposomes | t 0 | 210 ± 22 | 0.37 | +11 ± 2 | 123 ± 16 | 0.17 | +6 ± 2 |
| t 2/6h | 265 ± 24 | 0.50 | +12 ± 2 | 141 ± 16 | 0.23 | +7 ± 2 | |
| Nutriosomes | t 0 | 206 ± 40 | 0.22 | +11 ± 3 | 106 ± 8 | 0.11 | +8 ± 3 |
| t 2/6h | 363 ± 38 | 0.55 | +12 ± 3 | 112 ± 7 | 0.09 | +7 ± 3 | |
| EU-nutriosomes | t 0 | 153 ± 13 | 0.17 | +6 ± 1 | 109 ± 9 | 0.10 | +7 ± 2 |
| t 2/6h | 141 ± 16 | 0.23 | +7 ± 1 | 116 ± 11 | 0.11 | +6 ± 2 | |