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. 2019 Jan 8;11(1):23. doi: 10.3390/pharmaceutics11010023

Figure 2.

Figure 2

The Effect of 2 pre-selected derivatives on the uptake (A) and efflux (B) of [3H]-DNM in MCF-7/ADR cells. [3H]-DNM uptake and efflux were assayed after the incubation with each derivative (100 μM) for 2 h and 1 h, respectively. VER was used as a positive control. Control represents uptake or efflux of tritium-labeled P-gp substrate alone. Each data represents the mean ± S.D. (*, p < 0.05) from triplicate experiments.