Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The change in DNM IC50 value by 100 μM piperazine derivatives in vitro (The numerical data were represented the cell survival ratio).
| Category | Derivatives | DNM IC50 (μM) |
|---|---|---|
| Control | Negative control | 31.7 |
| Positive control * | 3.1 | |
| Piperazine derivatives | 1 | 5.4 |
| 2 | 7.6 | |
| 3 | 11.5 | |
| 4 | 2.7 |
* Positive control: VER, a P-gp inhibitor.
