Ac |
Acetyl |
AIDS |
Acquired immunodeficiency syndrome |
Ala |
Alanine |
AZT |
Azidothymidine |
BA |
Betulinic acid |
BA-AA |
Betulinic acid 3-acetyl acrylate |
BA-LEV |
Betulinic acid levulinate |
BA-M-LEV |
Methylated betulinic acid levulinate |
BN |
Betulin |
Bn |
Benzyl |
BoA |
Betulonic acid |
Boc |
tert-Butyloxycarbonyl |
BODIPY |
Boron-dipyrromethene |
Bu |
Butyl |
cat |
Catalyst |
CCID50
|
Cell culture infectious dose 50% |
CD |
Cyclodextrin |
CDI |
1,1’-Carbonyl-diimidazole |
CuAAC |
Copper-catalyzed azide-alkyne cycloaddition |
Dab |
2,4-Diaminobutyric acid |
Dap |
2,3-Diaminopropionic acid |
DCC |
N,N’-Dicyclohexylcarbodiimide |
DCM |
Dichloromethane |
DIC |
N,N’-Diisopropylcarbodiimide |
DIPEA |
N,N-Diisopropylethylamine |
DMA |
N,N-Dimethylacetamide |
DMAP |
4-(Dimethylamino)pyridine |
DME |
1,2-Dimethoxyethane |
DMF |
Dimethylformamide |
DMSO |
Dimethylsulfoxide |
DPPA |
Diphenyl phosphoryl azide |
EC50
|
Half maximal effective concentration |
EDC |
N-(3-Dimethylaminopropyl)-N’-ethylcarbodiimide |
equiv |
Molar equivalents |
Et |
Ethyl |
GI50
|
Growth inhibition of 50% of cells |
GSK |
GlaxoSmithKline |
HBA |
23-Hydroxybetulinic acid |
HIV |
Human Immunodeficiency Virus |
HOBt |
Hydroxybenzotriazole |
HPMA |
N-(2-Hydroxypropyl)methacrylamide |
IC50
|
Half maximal inhibitory concentration |
i-Pr |
Isopropyl |
KHMDS |
Potassium bis(trimethylsilyl)amide |
LTA |
Lead tetraacetate or lead(IV) acetate |
Lys |
Lysine |
mCPBA |
m-Chloroperoxybenzoic acid |
Me |
Methyl |
Orn |
Ornithine |
PCC |
Pyridinium chlorochromate |
PEG |
Polyethylene glycol |
Ph |
Phenyl |
Py |
Pyridine |
PyBOP |
Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate |
quant |
Quantitative (yield) |
rt |
Room temperature |
SN2 |
Bimolecular nucleophilic substitution |
TBS |
tert-Butyl(dimethyl)silyl |
TBTU |
N,N,N’,N’-Tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborate |
t-Bu |
tert-Butyl |
Tf |
Triflate |
TFA |
Trifluoroacetic acid |
THF |
Tetrahydrofuran |
UA |
Ursolic acid |
β-CD |
β-Cyclodextrin |