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. 2019 Jan 9;20(2):233. doi: 10.3390/ijms20020233

Figure 6.

Figure 6

Skeletal muscle mitochondrial energy metabolism modulation in ALS untrained and ALS swim-trained mice, based on Desseille et al. [26], Tefera et al. [40] and our results. Black arrows indicate changes observed in skeletal muscle of ALS mice at symptomatic stage of disease vs. ALS 0 or WT. Red arrows indicate swim-training-induced changes in skeletal muscle of ALS mice at symptomatic stage of disease vs. untrained symptomatic ALS mice. ↑—increased; ↓—decreased; --—no changes. CS—citrate synthase, IDH—Isocitrate dehydrogenase, OGDH—2-oxoglutarate dehydrogenase, MDH—malate dehydrogenase, I, II, III, IV—complexes of mitochondrial electron transfer chain.