Figure 6.

Schematic representation of altered metabolites during systemic inflammatory response under BSI condition. Blood delivers the glucose to tissues, where it reaches cells through diffusion and by glucose transporters. Glucose is converted to G6P and then pyruvate through glycolysis, leading to lactate accumulation as well as an elevated tricarboxylic acid cycle. The altered metabolites are shown in yellow. Red and blue arrows represent SE + TPN and SE + COL, respectively, and denote higher and lower levels of the respective metabolites compared to controls.