ATO |
arsenic trioxide |
APL |
acute promyelocytic leukemia |
HPLC-ICP-MS |
high performance liquid chromatography coupled to inductively coupled plasma mass spectrometry |
iAs |
inorganic arsenic |
AsIII
|
arsenite |
AsV
|
arsenate |
MMAV
|
monomethylarsonic acid |
DMAV
|
dimethylarsinic acid |
MMAIII
|
methylarsonous acid |
DMAIII
|
dimethylarsinous acid |
i.v. |
intravenous administration |
i.g. |
intragastrical administration |
SD |
standard deviation |
Cmax
|
maximum concentration |
Tmax
|
time of maximum concentration |
AUClast
|
area under the curve from the time of dosing to the last measurable concentration |
AUCINF_obs
|
AUC from dosing time extrapolated to infinity |
CL_obs
|
total clearance |
Vss_obs
|
volume of distribution at steady state |
MRTlast
|
mean residence time |