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Experimental setup adopted by Whitley et al. [100]. The single-stranded DNA (ssDNA) binding site (black in the figure) is connected by means of two spacers (red) and two double-stranded DNA (dsDNA) handles (blue) to two trapped beads. Binding events of the tagged oligonucleotides are identified by confocal fluorescence. Reprinted with permission from [100]. Copyright 2018 American Physical Society.
