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. 2019 Jan 11;20(2):278. doi: 10.3390/ijms20020278

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Antibacterial strategy using dual agents in dental composite. Dimethylaminohexadecyl methacrylate (DMAHDM) can inactivate periodontal pathogens by contact without leaching from resins. Methacryloyloxyethyl phosphorylcholine (MPC) can detach proteins, thereby hampering bacterial attachment. DMAHDM and MPC are both non-volatile, chemically stable and can sustain long-term antibacterial activity. DMAHDM: dimethylaminohexadecyl methacrylate; MPC: 2-methacryloyloxyethyl phosphorylcholine; NACP: nanoparticles of amorphous calcium phosphate (Revised and resubmitted to Dent. Mater. Ref [132].)