Table 1.
Polymeric materials as drug delivery systems for combating periodontal pathogens.
| Type | Polymer/Polymer-Based Product | Drug/Antibiotics | Periodontal Pathogens | References |
|---|---|---|---|---|
| Film | Chitosan | Chlirhexidine (Chx) gluconate Taurine (Amino acid) | P. gingivalis | [9] |
| Cellulose acetate phthalate and Pluronic F-127 (CCAP) | Metronidazole | >P. gingivalis | [55] | |
| PLGA | Secnidazole (SC) Doxycycline hydrochloride (DH) |
P. gingivalis
F. nucleatum |
[56] | |
| Gel | Arestin® | Minocycline | >A. actinomycetemcomitans | [57] |
| Polyester | Doxycycline hyclate Metronidazole | >P. gingivalis | [46] | |
| Badam gum Karaya gum Chitosan |
Moxifloxacin | >A. actinomycetemcomitans | [58] | |
| Atridox® | Doxycycline hyclate |
P. gingivalis
F. nucleatum |
[59,60] | |
| Chip | PLGA | Chlorhexidine (CHX) CHX digluconate |
P. gingivalis | [61] |
| Strip | Hydroxypropylcellulose | Green tea catechin |
P. gingivalis Prevotella spp. |
[62] |
| Cube | poly(glycerol sebacate) (PGS) | Berbereine chlorhexidine |
P. gingivalis
A. actinomycetemcomitans |
[63] |
| Microparticles | Gelatin | Doxycycline | P. gingivalis | [64] |
| Nanoparticles | PLGA Polymersomes |
Minicycline Metronidazole Doxicycline |
P. gingivalis
T. forsythia T. denticola P. gingivalis |
[65,66] |
| PEGylated PLGA | Minocycline | A. actinomycetemcomitans | [67] | |
| PLGA | H.madagascariensis leaf extract (HLE) | Prevotella species | [68] |