Table 1.
Intrinsic endoplasmic reticulum stress markers identified in mammalian oocytes and preimplantation embryos.
| Species | Stage (Derivation) | ER Stress Markers | Refs | |
|---|---|---|---|---|
| Genes | Proteins | |||
| Mouse | Oocytes | ATF4, ATF6 and BiP/GRP78 | [30] | |
| Mouse | Oocytes | XBP1, ATF4, ATF6 and HSPA5 | [29] | |
| Mouse | Oocytes (vitrified) | XBP1 | [40] | |
| Mouse | Oocytes/blastocysts | XBP1-u and XBP1-s | XBP1 | [16] |
| Mouse | Blastocysts | ATF4, ATF6, BiP, CHOP and PERK | [37] | |
| Mouse | Blastocysts | XBP1, BIP, IRE1, ASK1, ATF4, ATF6, CHOP and PERK | [26] | |
| Mouse | Blastocysts | XBP1 | BiP | [31] |
| Pig | Oocytes | BiP, ATF4, XBP1-u, XBP1-s and CHOP | ATF4, ATF6, BiP/GRP78, P90ATF6, P50ATF6 and CHOP | [3] |
| Pig | Oocytes and 1-cell to blastocyst-stage embryos (PA) | XBP1-u and XBP1-s | XBP1 | [4] |
| Pig | Embryos (day 5)/blastocysts (PA) | XBP1 and GRP78 | [38] | |
| Pig | Blastocysts (SCNT) | XBP1-u and XBP1-s | XBP1 | [13] |
| Bovine | Blastocysts (IVF) | XBP1-u, XBP1-s, IRE1, ATF4, ATF6 and CHOP | [12] | |
| Bovine | Blastocysts (IVF and SCNT) | XBP1-u, XBP1-s and CHOP | [15] | |
| Bovine | Blastocysts (IVF and SCNT) | XBP1, BiP/GRP78, EDEM, ATF4, ATF6, CHOP and IRE1 | [39] | |
| Bovine | Blastocysts (SCNT) | BiP, CHOP and IRE1 | [41] | |
| Buffalo | Blastocysts (IVF) | GRP78 and GRP94 | [14] | |
| Sheep | Oocytes | ATF4, ATF6, GRP78 and CHOP | [42] | |
Refs: References.