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Kinetic analysis results for target molecule 4a. (a) Lineweaver-Burk plots for the inhibition of urease in the presence of compound 4a. Concentrations of 4a of 0, 0.75, 1.5, 3, and 6 µM, respectively. Substrate urea concentrations were 1.57, 3.12, 6.25, 12.5, 25, and 50 µM, used respectively; (b) The secondary replot of the Lineweaver-Burk plot, slope vs. various concentrations of 4a.
