Table 1.
Liver function tests (LFTs) performed on the plasma of various groups after three weeks of treatment with turmeric NPs (T-NPs) in comparison with standard allopurinol (Allp) treatment. The results are shown as mean ± SD of 6 experiments, and p < 0.05 were considered statistically significant.
| Parameter | Unit | Normal Range | Control Group | Diseased Group | Allp-Treated Group (50 mg) |
T-NPs Treated Group (5 ppm) |
T-NPs Treated Group (10 ppm) |
T-NPs Treated Group (20 ppm) |
|---|---|---|---|---|---|---|---|---|
| ALT | U/L | 10–40 | 34 ± 6.48 a | 61.16 ± 9.40 b | 51 ± 5.01 b | 48 ± 9.16 | 63 ± 5.35 b | 42 ± 11.3 |
| AST | U/L | 10–40 | 36 ± 3.55 a | 55.83 ± 7.31 b | 45.16 ± 2.13 | 49 ± 5.53 | 68 ± 2.58 b | 50 ± 3.21 b |
| Total bilirubin | mg/dL | 0.2–1.0 | 0.46 ± 0.16 | 0.41 ± 0.10 | 0.41 ± 0.09 | 0.5 ± 0.16 | 0.5 ± 0.12 | 0.6 ± 0.08 |
| ALP | U/L | 65–306 | 189 ± 22.99 | 183.33 ± 53.60 | 171 ± 18.97 | 69 ± 3.78 ab | 328 ± 35.59 ab | 142 ± 31.28 |
Where “a” and “b” showed a statistically significant difference when the treatments were compared with the disease and control groups, respectively. ALT-alanine aminotransferase. AST-aspartate aminotransferase. ALP-alkaline phosphatase.