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. 2019 Jan 2;9(1):8. doi: 10.3390/metabo9010008

Figure 8.

Figure 8

Schematic representation of the proposed biosynthetic pathway of defence-related flavonoids in sorghum. This pathway displays some of the flavonoids annotated in sorghum plant extracts following infection with B. andropogonis. Solid lines represent main routes and dashed lines represent alternative routes. Abbreviations: PAL = phenylalanine ammonia lyase; C4H = cinnamate 4-hydroxylase; CCL = coumaryl-CoA ligase; CHS = chalcone synthase; CHI = chalcone isomerase; 7GT = flavanones-7-O-glucosyltransferase; Cm1,2RhaT = 1,2 rhamnosyltransferase; F2HI = flavanone-2-hydrohlyase; FNS = flavone synthase; OGT = O-glycosyltransferase; FRG = flavanones 7-O-glucoside-2”-O-β-l-rhamnosyltransferase; LGR = luteolin 2-O-β-l-rhamnosyltransferase; VRM = vitexin 2”-O-rhamnoside 7-O-methyltransferase; MT = methyltransferase; FND = flavanones 3-dioxygenase; FLS = flavonol synthase; FGT = flavonoid 3-O-glucosyltransferase; FGRT = flavonol-3-O-glucoside l-rhamnosyltransferase; FHS = flavonoid 3’,5’-hydroxylase; CGT = C-glycosyl transferase; HGD = 2-hydroxynaringenin-6-C-glucoside dehydratase; DH = dehydrogenase; ? = enzymes not yet characterised. Metabolites annotated in this study are in italics. Flavones and derivatives are indicated in purple and the flavanone precursors in yellow.