Table 5.

Results of AFA entrapment in buccal and sublingual mucosae after administration of solution and films.

Sample	Administered AFA Dose	AFA (mg) ± SE into Buccal Mucosa after 4 h	% of Dose into Buccal Mucosa after 4 h	AFA (mg) ± SE into Sublingual Mucosa after 2 h	% of Dose into Sublingual Mucosa after 2 h
Solution	15 mg/mL in saliva	0.361 ± 0.074	2.40	0.535 ± 0.087	3.56
AFA100	2.4 ± 0.4 mg in 0.4 mL saliva	0.449 ± 0.181	18.70	0.612 ± 0.071	25.50
AFA300	6.5 ± 0.5 mg in 0.4 mL saliva	0.455 ± 0.093	8.24	0.648 ± 0.086	11.52