Table 1.

Antimicrobial activity of natural CDXs with furan groups.

No.	Name/Structure	Antimicrobial Activity (MIC)
1N	Mangostanin	Mycobacterium tuberculosis H37Ra (25 µM)
2N	Toxyloxanthone-C	Candida albicans (25 µM); Candida glabrata (8 µM); Aspergillus fumigatus (8 µM); Aspergilus nidulans (8 µM); Cryptococcus neoformans (8 µM); Bacillus substilis PCI-219 (3.13 µM); MSSA JMC-2874 (6.25 µM); MRSA (6.25 µM); Micrococcus Luteus (12.5 µM)
3N	Gerontoxanthone-G	B. subtilis PCI-219 (12.5 µM); MSSA JMC-2874 (12.5 µM); MRSA (12.5 µM); M. luteus (12.5 µM)
4N	Gerontoxanthone-A	B. subtilis PCI-219 (<25 µM); MSSA JMC-2874 (<25 µM); MRSA (<25 µM); M. luteus (<25 µM); Enterococcus faecalis (VSE) (>25 µg/mL); E. faecalis (VanA) (>25 µg/mL); E. faecalis (VanB) (>25 µg/mL); Enterococcus gallinarum (VanC) (>25 µg/mL)
5N	Formoxanthone-C	B. Substilis (4.6 µM); S. aureus (2.3 µM); Streptococcus faecalis (18.7 µM); Salmonella Typhi (4.6 µM)

MIC: Minimum inhibitory concentration; MRSA: Methicillin-resistant S. aureus; MSSA: Methicillin-sensitive S. aureus; * Stereogenic center.