Table 7.

Antimicrobial activity of muchimangins analogues.

No.	Structure	${[\mathsf{\alpha }]}_{\mathbf{D}}^{24}(\mathbf{c})$ a	Antimicrobial Activity (MIC)
1S		±	S. aureus (10.0 µM); B. subtilis (50.0 µM)
		+2.5 (0.02)	S. aureus (10.0 µM); B. subtilis (50.0 µM)
		−28.0 (0.02)	S. aureus (12.5 µM); B. subtilis (100.0 µM)
2S		±	S. aureus (10.0 µM); B. subtilis (12.5 µM)
		+	S. aureus (10.0 µM); B. subtilis (10.0 µM)
		-	S. aureus (10.0µM); B. subtilis (12.5 µM)
3S		±	S. aureus (25.0 µM); B. subtilis (>100.0 µM)
		+	S. aureus (10.0 µM); B. subtilis (>100.0 µM)
		-	S. aureus (50.0 µM); B. subtilis (>100.0 µM)
4S		±	S. aureus (>100 µM); B. subtilis (>100.0 µM)
5S		±	S. aureus (>100 µM); B. subtilis (>100.0 µM)

MIC: Minimum inhibitory concentration; ^a Specific rotation measured in CHCl₃; * Stereogenic center; Enantioselectivity is represented by: “±” racemate; “-“ levorotatory; “+” dextrorotatory.