Table 12.
Antimicrobial activity of derivatives of caged xanthones.
| No. | Structure | Antimicrobial Activity (MIC or Inhibitory Growth Zones *) |
|---|---|---|
| 64S |
|
MRSA USA300 SF8300 (22.24 mm; 25 µM); MSSA ATCC 25923 (19.99 mm; 12.5 µM) |
| 65S |
|
MRSA USA300 SF8300 (16.27 mm; 25 µM); MSSA ATCC 25923 (17.07 mm; 12.5 µM) |
| 66S |
|
MRSA USA300 SF8300 (6.27 mm); MSSA ATCC 25923 (6.53 mm) |
| 67S |
|
MRSA USA300 SF8300 (6 mm); MSSA ATCC 25923 (6 mm) |
| 68S |
|
MRSA USA300 SF8300 (9.53 mm); MSSA ATCC 25923 (7.09 mm) |
| 69S |
|
MRSA USA300 SF8300 (18.34 mm; 25 µM); MSSA ATCC 25923 (16.52 mm; 25 µM) |
| 70S |
|
MRSA USA300 SF8300 (6.28 mm); MSSA ATCC 25923 (6.09 mm) |
| 71S |
|
MRSA USA300 SF8300 (19.35 mm; 25 µM); MSSA ATCC 25923 (15.91 mm; 25 µM) |
| 72S |
|
MRSA USA300 SF8300 (15.91 mm; 100 µM); MSSA ATCC 25923 (13.08 mm; 50 µM) |
| 73S |
|
MRSA USA300 SF8300 (8.21 mm); MSSA ATCC 25923 (6.89 mm) |
| 74S |
|
MRSA USA300 SF8300 (9.09 mm); MSSA ATCC 25923 (7.50 mm) |
| 75S |
|
MRSA USA300 SF8300 (6 mm; 25 µM); MSSA ATCC 25923 (6 mm; 12.5 µM) |
* The antimicrobial studies were determined by disc diffusion method; MIC: Minimum inhibitory concentration; MRSA: Methicillin-resistant S. aureus; MSSA: Methicillin-sensitive S. aureus.