Table 1.
Effects of OA and Met (n = 6, per group) on heart sizes, body weights and cardiac CRP of rats that continued with HFHC diet. Values are presented as standard error of mean ± SEM. Non-pre-diabetes control (NC), pre-diabetes control (PC), metformin treated (Met), Metformin treated with dietary intervention (Met + DI), oleanolic acid treated (OA) and oleanolic acid treated with dietary intervention (OA + DI).
| Experimental Group | Heart Weights (g) | Body Weights (g) | Heart/Body Ratio (H/B) | Cardiac CRP (ng/mL) |
|---|---|---|---|---|
| NC | 1.56 ± 0.08 | 387.50 ± 11.18 | 0.0040 ± 0.00029 | 9.63 ± 1.08 |
| PC | 1.72 ± 0.05 * | 679.75 ± 78.52 * | 0.0027 ± 0.00029 * | 17.24 ± 0.35 * |
| Met | 1.62 ± 0.03 α | 500.50 ± 2.59 *α | 0.0032 ± 0.00028 α | 16.61 ± 0.17 * |
| Met + DI | 1.73 ± 0.01 * | 443.00 ± 13.86 *α | 0.0039 ± 0.00012 α | 15.03 ± 0.27 * |
| OA | 1.61 ± 0.12 α | 516.75 ± 8.28 *α | 0.0031 ± 0.00019 α | 12.10 ± 0.45 α |
| OA+DI | 1.49 ± 0.04 α | 434.25 ± 12.19 α | 0.0034 ± 0.00011 α | 9.56 ± 0.58 α |
* p < 0.05 denotes comparison with NC; α p < 0.05 denotes comparison with PC.