Fig. 2.

Hsa_circ_0081143 promoted GC cells proliferation, invasion, and cisplatin resistance. a Relative expression of hsa_circ_0081143 in GC cells transfected with si-circ_0081143 and si-NC. b, c Has-circ_0081143 inhibition decreased the proliferation and colony formation ability in GC cells. d Has-circ_0081143 inhibition induced GC cells apoptosis rate. e Has-circ_0081143 inhibition reduced GC cells invasion ability. f Has-circ_0081143 reduction increased the sensitivity of GC cells to cisplatin. g The tumor volumes were measured every week. h Photographs of tumor xenografts excised 6 weeks. i Tumor weight was measured after mouse was surgically dissected. *P < 0.05