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. 2019 Feb 1;9:15. doi: 10.1186/s13578-019-0277-z

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 10 — NVD and FH535 administration induces apoptosis in HCT116 xenograft tumors in athymic nude mice. a Effect of NVD and FH535 treatment (15 and 25 mg/kg) on protein expression of cleaved Caspase 3 of HCT116 implanted xenografts tumors in athymic nude mice. b, c Immunohistochemistry of cleaved Caspase 3 of NVD and FH535 administrated tumor xenograft vs untreated control tumor xenografts. The data are representative of three independent experiments with similar results