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. 2019 Feb 1;9:15. doi: 10.1186/s13578-019-0277-z

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 12 — Effect of NVD and FH535 administrated on HCT116 xenograft tumors for protein expression. a Expression of Akt, β-Catenin and Survivin protein by immunobloting in NVD administrated and control group, experiment performed in triplicate. b Effect of NVD and FH535 administrated on protein expression of β-Catenin and control as detected by immunohistochemical staining. Data are presented as the mean ± SD. **P < 0.01. (Scale bar, 100 µm). c Effect of NVD on expression of mRNA of β-Catenin by RT-PCR