Table IV.
Comparison of the Mutation Frequencies for All Mutation Types and for Three Major Types of Mutations in the Liver cII Gene of Mice Treated With AFB1 as
Treatment group | Total dose | Mutation frequencies (X10−6) |
|||
---|---|---|---|---|---|
All types | G:C → A:T | G:C → T:A | Frameshift | ||
Neonate | 0 | 28 | 14 | 6 | 4 |
6 | 688 | 62 | 489 | 28 | |
Adult | 0 | 42 | 17 | 3 | 10 |
60 | 66 | 21 | 16 | 5 |
The unit for total dose is mg AFB1/kg body weight.