Fig. 3.
(A) Comparison of the percentage of mutational types for all (large and small) colonies produced in mouse lymphoma cells treated with 11 CSCs or control (DMSO). The mutants were obtained from the highest dose of 11 CSCs with RTG of 12–27% in Table III. The data are the weighted sum of mutation percentages from large and small colonies (see Table III for the proportion of small-colony mutants). The ‘→’ indicates the LOH extends from Tk locus to other three loci (D11Mit36, D11Mit20 and D11Mit74). (B) The loci that were analysed for LOH (Tk1, D11Mit36, D11Mit20 and D11Mit74) are marked on the chromosome 11, and the locus of D11Mit74 is located at the top of the chromosome 11.