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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Drug Alcohol Depend. 2018 Oct 22;195:170–177. doi: 10.1016/j.drugalcdep.2018.09.005

Table 1.

Prevalence of DSM-5 cannabis withdrawal symptoms experienced in the past 12-month among frequent cannabis usersa

Cannabis withdrawal symptom Frequent cannabis users
(N=1,527)
Frequent cannabis users with
DSM-5 CWSb (N=184)
Prevalence % (SE)
Nervousness or anxiety 12.9 (1.28) 76.3 (3.63)
Hostility (i.e., irritability, anger or aggression) 13.6 (1.30) 71.9 (4.60)
Sleep difficulty 14.4 (1.12) 68.2 (4.08)
Depressed mood 10.9 (1.09) 58.9 (4.92)
Restlessness 6.6 (0.89) 43.1 (4.62)
Decreased appetite/weight loss 4.5 (0.61) 26.7 (3.99)
Any physical symptom 16.2 (1.27) 70.4 (4.81)
 Headache 11.7 (0.98) 47.9 (4.82)
 Shakiness/tremors 3.8 (0.64) 24.7 (4.00)
 Sweating 3.6 (0.67) 22.0 (4.35)
 Abdominal pain 2.5 (0.49) 12.1 (2.72)
 Chills 1.6 (0.42) 6.7 (2.15)
 Fever 0.8 (0.24) 3.1 (1.15)
a

Cannabis use 3 or more days/week in the past year (DSM-5 criterion A of “heavy, prolonged use”).

b

CWS=cannabis withdrawal syndrome; DSM-5 criterion B for CWS: 3 or more of 7 symptoms, occurring within 1 week after cessation or reduction of cannabis use.