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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Mol Cancer Res. 2018 Nov 16;17(2):604–617. doi: 10.1158/1541-7786.MCR-18-0750

Figure 7. SRC and PKC inhibition block CCL2 induced growth of basal-like breast cancer cells.

Figure 7.

A. MCF10CA1d breast cancer cells were treated with 100 ng/ml CCL2 in the presence or absence of DMSO vehicle control, PP2 or Gö 6983 for 15 minutes and analyzed for expression of the indicated proteins by immunoblot. B-C. Breast cancer cells were treated with CCL2 in the presence or absence of 10 μM PP2 or 5 μM Gö 6983 for 24 hours and analyzed for PCNA (B) or p27KIP1 expression (C) by immunofluorescence staining. Statistical analysis was performed using One Way ANOVA with Bonferroni post-hoc comparison. Statistical significance was determined by p<0.05. *p<0.05, **p<0.01, ***p<0.001. Mean±SEM are shown.