Table 1.
Timeline of the introduction of new antibiotics and the first reports of resistance emerging.
| Antibiotic introduced | Antibiotic resistance identified | ||
|---|---|---|---|
| 1943 | penicillin | 1940 | penicillin-resistant Staphylococcus |
| 1950 | tetracyline | 1959 | tetracycline-resistant Shigella |
| 1953 | erythromycin | 1978 | erythromycin-resistant Pneumococcus |
| 1960 | methicillin | 1962 | methicillin-resistant Staphylococcus |
| 1967 | gentamycin | 1979 | gentamycin-resistant Enterococcus |
| 1972 | vancomycin | 1988 | vancomycin-resistant Enterococcus |
| 1985 | ceftazidime | 1987 | ceftazidime-resistant Enterobacteriaceae |
| 1985 | imipenem | 1998 | imipenem-resistant Enterobacteriaceae |
| 1996 | lefloxacin | 1996 | lefloxacin-resistant Pneumococcus |
| 2000 | linezolid | 2001 | linezolid-resistant Staphylococcus |
| 2003 | daptomycin | 2005 | daptomycin-resistant Staphylococcus |
| 2010 | ceftaroline | 2011 | ceftaroline-resistant Staphylococcus |