Table 2.
Statistics including correlation with age for 10 analytes
| Variable | 20’s N = 13 |
30’s N = 13 |
40’s N = 13 |
P by Kruskal-Wallis test | P value for pairwise comparison* | Spearman’s correlation with age | P | ||
|---|---|---|---|---|---|---|---|---|---|
| 20’s vs 30 ‘s | 20’s vs 40 ‘s | 30’s vs 40 ‘s | |||||||
| PDGF-BB (ng/mL) | 3.3 [2.4, 6.5] | 3.5 [1.4, 6.2] | 2.1 [1.4, 4.9] | 0.030 | 0.72 | 0.013 | 0.094 | −0.32 | 0.049 |
| TGF-β1 (ng/mL) | 15.4 [11.0, 24.7] | 17.1 [11.4, 31.9] | 13.1 [11.2, 21.1] | 0.12 | – | – | – | −0.17 | 0.295 |
| VEGF (pg/mL) | 104 [21, 534] | 290 [65, 591] | 196 [41, 725] | 0.20 | – | – | – | 0.19 | 0.325 |
| EGF (pg/mL) | 722 [489, 923] | 861 [489, 1736] | 612 [226, 938] | 0.029 | 0.10 | 0.18 | 0.026 | −0.19 | 0.255 |
| FGF (pg/mL) | 11 [5, 15] | 12 [4, 40] | 10 [4, 19] | 0.33 | – | – | – | −0.20 | 0.211 |
| HGF (pg/mL) | 431 [285, 596] | 492 [357, 733] | 451 [338, 560] | 0.11 | – | – | – | 0.16 | 0.341 |
| IGF-1 (ng/mL) | 90 [58, 139] | 70 [60, 96] | 63 [47, 104] | 0.027 | 0.18 | 0.024 | 0.10 | −0.39 | 0.014 |
| PLT (×104/μL) | 23 [16, 26] | 26 [20, 34] | 21 [18, 32] | 0.004 | 0.003 | 0.94 | 0.024 | 0.03 | 0.87 |
| PLT (PRP) (×104/μL) | 39 [28, 56] | 47 [32, 82] | 34 [23, 49] | 0.004 | 0.077 | 0.16 | 0.001 | −0.23 | 0.151 |
Values in the table are shown as median [minimum, maximum]
PDGF-BB platelet-derived growth factor-BB, TGF-β1 transforming growth factors-β1, VEGF vascular endothelial growth factor, EGF epidermal growth factor, FGF fibroblast growth factor, HGF hepatocyte growth factor, IGF-1 insulin-like growth factor-1
*Fisher’s LSD for multiplicity adjustment