Figure 3.

MaR1 reduced TNF-α, IL-6, and ALT/AST levels in CLP-induced septic mice. Blood samples were collected after CLP surgery at 24 h time point and then centrifuged at 3000 g for 10 min to collect serum. (a, b) The serum levels of TNF–α and IL-6 were, respectively, determined using ELISA kits. (c, d) Then, the levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in blood were determined by biochemistry assay kits. Data are presented as mean ± SD. ^∗P < 0.05 and ^∗∗P < 0.01, n = 5 per group.