Table 2:
Medication Use Frequency for participants with and without Polypharmacy
| Medication | All N=325 n (%) |
Polypharm N=104 n (%) |
No Polypharm N= 221 n (%) |
P value |
|---|---|---|---|---|
| Non-Prescription Drug | 162(53.5) | 82(78.8) | 80(36.2) | <0.001 |
| HMGCoA Inhibitorsa | 168(51.7) | 76(73.1) | 92(41.6) | <0.001 |
| Beta Blockers | 86(26.5) | 51(49.0) | 35(15.8) | <0.001 |
| Ace Inhibitors | 67(20.6) | 31(29.8) | 36(16.3) | 0.008 |
| Antiplatelet Agents | 59 (18.2) | 35(33.7) | 24(10.9) | <0.001 |
| Angiotensin Receptor Blockers | 60(18.5) | 29(27.9) | 31(14.0) | <0.005 |
| Vitamin and Mineral Combinations | 32(9.8) | 21(20.2) | 11(5.0) | <0.001 |
| Oral hypoglycemic Agents | 43 (13.2) | 24(23.1) | 19(8.6) | 0.001 |
| Thyroid Hormone Replacements | 38 (11.7) | 19 (18.3) | 19(8.6) | 0.016 |
| Calcium | 34(10.5) | 20(19.2) | 14(6.3) | <0.001 |
| Vitamin D | 27 (8.3) | 18(17.3) | 9(4.1) | <0.001 |
| Proton Pump Inhibitors | 20 (6.2) | 13(12.5) | 7(3.2) | <0.002 |
| Antihypertensive Combination | 21(6.5) | 9(8.7) | 12(5.4) | 0.333 |
| Ophthalmic Agents | 21 (6.5) | 11(10.6) | 10(4.5) | 0.052 |
| Anticoagulants | 23(7.1) | 16(15.4) | 7(3.2) | <0.001 |
| Agents for Gout | 18(5.5) | 14(13.5) | 4(1.8) | <0.001 |
| NSAID analgesic | 14(4.3) | 5(4.8) | 9(4.1) | 0.774 |
| Loop Diuretic | 14(4.3) | 9 (8.7) | 5(2.3) | <0.015 |
| Thiazide diuretic | 17(5.2) | 12(11.5) | 5(2.3) | 0.001 |
| High Risk Medications | 51(15.7) | 29(27.9) | 22(10) | <0.001 |
| Antidepressants | 15(4.6) | 8(7.7) | 7(3.2) | 0.089 |
| Alpha 1 antagonists | 5(1.5) | 4(3.8) | 1(0.5) | 0.038 |
| Benzodiazepines/anxiolytics | 13(4.0) | 9(8.7) | 4(1.8) | 0.006 |
| Antihistamines | 6(1.8) | 3(2.9) | 3(1.4) | 0.389 |
| Opioids | 3(0.9) | 3(2.9) | 0 (0) | 0.032 |
| Anticholinergics | 2(0.6) | 2(1.9) | 0(0) | 0.102 |
| Muscle relaxants | 1(0.3) | 1(1.0) | 0(0) | 0.320 |
a
HMGCoA: 3-hydroxy-3-methyl-glutaryl-coenzyme A