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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Joint Bone Spine. 2018 Aug 3;86(3):301–307. doi: 10.1016/j.jbspin.2018.07.004

Figure 2. Adenosine receptors and signaling pathways.

Figure 2.

The A1 and A2A receptors are the high affinity adenosine receptors while the A2AB and A3 receptors are lower affinity receptors. Demonstrated in the figure are the different coupled G-proteins with each adenosine receptor and some of the effects this signaling has on certain immune cells. Adapted from Cronstein andSitkovsky (2017) (14).