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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: IEEE Trans Vis Comput Graph. 2018 Mar 27;25(4):1760–1773. doi: 10.1109/TVCG.2018.2818701

Fig. 2.

Fig. 2.

Heterogeneity in microvessel structure. Examples of mouse microvessels stained using Collagen IV antibody, from age-matched wild-type (a) and 12-month-old APdE9 (Alzheimer’s Disease) (AD) models (b). Close-ups show vessel sparsity and fragmentation (fr) in the AD model (c-d). Structural variations are also seen in different brain regions, including caudoputamen (e) and basolateral amygdaloid nucleus (f).