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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Invest New Drugs. 2018 Aug 3;37(2):364–374. doi: 10.1007/s10637-018-0647-0

Fig. 4.

Fig. 4

Simulation for Apra S10 doses to achieve a concentration above 40 ng/mL. The dosing intervals considered were (a) daily, (b) every other day. The dashed horizontal lines (red) represent the minimum effective concentration, 40 ng/mL.