Figure 132.

(Top) Sengupta and Dey evaluated the role of the Cu ion and heme axial base ligation in three electrode-immobilized heme(-Cu) systems on electrocatalytic selectivity (%PROS released) for the reduction of O₂ at both fast (EPG electrode) and slow (C₈SH and C₁₆SH SAM coated gold electrodes) electron transfer rates. Distinct pathways for PROS production were proposed for hydroxo-bridged heme-copper complexes without (Scheme 1) and with (Scheme 2) an axial imidazole ligand. Adapted from ref 1051. Copyright 2015 American Chemical Society.