Figure 141.
(A) Plot showing O2-consumption over time for the MnII-, FeII-, and CoII-bound FeBMb models as well as for the case in which the nonheme site is empty (black trace); initial rates are included in (C). (B) O2-consumption rates for the same four variants as a function of the final products, H2O versus reactive oxygen species such as superoxide or peroxide. (C) Tabulated parameters including metal dissociation constants, initial rates of O2-consumption, total turnover numbers, and percentage of ROS formation for the four variants showing the trends described in the text. Adapted from ref 1098. Copyright 2017 American Chemical Society.