Figure 143.

(Top) Myoglobin crystal structure and the heme-types which can be incorporated into modified Mb models (including hemes b and a, native to Mb and CcOs, respectively, plus synthetic variations) and their reduction potentials (vs SHE). (Bottom) Plot of oxidase activity (measured using an O₂ electrode) as a function of heme reduction potential, in reference to wild-type Mb and bovine CcO. Adapted from ref 1107. Copyright 2014 American Chemical Society. Adapted with permission from ref 1102. Copyright 2017 Wiley-VCH.